NDBM
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2958641-42-2
- 화학식: C33H35BrN4O7
- 분자량:679.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Pim-1[1]
NDBM (2.5, 5, 10 and 20 μM, 18 h) decreases the survival rate of tumor cells (MGC-803, HepG2 and Hela) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2958641-42-2
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분자량 679.56
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화학식 C33H35BrN4O7
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SMILES
BrC1=CC=C2OC(C(NCCOCCOCCN3C(C4=C5C(C(NCCN6CCOCC6)=CC=C5C3=O)=CC=C4)=O)=O)=CC2=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)