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Cat. No.: HY-W650803

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Nemazoline

(Synonyms: A-57219 free base; SCH 40054 free base)

Nemazoline (A-57219) is selective α-adrenergic agent with α₁-agonist/α₂-antagonist activity, which is used as a nasal decongestant. Nemazoline produces decongestion by α₁-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of α₂-antagonism. Nemazoline also blocks endogenous noradrenaline-mediated α ₂-constriction of the resistance vessels.

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CAS No.: 130759-56-7
화학식: C₁₀H₁₁Cl₂N₃
분자량:244.12

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Nemazoline Chemical Structure

CAS No.: 130759-56-7

사이즈

가격

재고

수량

Sample (0.1mg)

In-stock

(In Japan)

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

α1-adrenergic receptor

α2-adrenergic receptor

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 130759-56-7
분자량 244.12
화학식 C₁₀H₁₁Cl₂N₃
SMILES

NC1=C(C=C(C=C1Cl)CC2=NCCN2)Cl
Synonyms

A-57219 free base; SCH 40054 free base
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. DeBernardis JF, et al. A new nasal decongestant, A-57219: a comparison with oxymetazoline. J Pharm Pharmacol. 1987 Sep;39(9):760-3. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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