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Cat. No.: HY-169950

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NMDA agonist 1

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM.

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CAS No.: 2576586-47-3
화학식: C₁₂H₁₃N₃O₃S
분자량:279.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NMDA agonist 1 Chemical Structure

CAS No.: 2576586-47-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
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Biological Activity

제품 설명

NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a K_i value of 96 nM. NMDA agonist 1 acts as a partial agonist of the GluN1/GluN2B complex with an EC₅₀ value of 78 nM^[1].

IC₅₀ & Target^[1]

NMDA Receptor

96 nM (Ki)

All iGluR Isoforms :

Chemical Information

CAS No. 2576586-47-3
분자량 279.31
화학식 C₁₂H₁₃N₃O₃S
SMILES

O=C([C@@H](CNC(C1=CC2=NC=CC(C)=C2S1)=O)N)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ascic E, et al. Advancements in NMDA Receptor-Targeted Antidepressants: From d-Cycloserine Discovery to Preclinical Efficacy of Lu AF90103. J Med Chem. 2024 Nov 28;67(22):20135-20155. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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NMDA agonist 1

All iGluR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NMDA agonist 1 Related Classifications

HY-169950 Related Classifications