OPC-4392
OPC-4392 is a orally active presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models. OPC-4392 can be used as antipsychotic agent.
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- CAS No.: 111073-34-8
- 화학식: C24H29N3O2
- 분자량:391.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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All Dopamine Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 111073-34-8
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분자량 391.51
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화학식 C24H29N3O2
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SMILES
CC(C(C)=CC=C1)=C1N(CC2)CCN2CCCOC3=CC=C(C=CC4=O)C(N4)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Yasuda Y, et al. 7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. Life Sci. 1988;42(20):1941-54. [Content Brief]
[2]. Murasaki M, et al. Phase 1 study of a new antipsychotic drug, OPC-4392. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(5):793-802. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
OPC-4392 Related Classifications
HY-106781 Related Classifications
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