OPC 4392 hydrochloride
Based on 1 Customer Validation
OPC 4392 hydrochloride is an agonist for presynaptic dopamine receptor and an antagonist for postsynaptic D2 receptor. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 1329509-60-5
- Formula: C24H30ClN3O2
- Molecular Weight:427.97
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Dopamine Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 1329509-60-5
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Appearance Solid
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Molecular Weight 427.97
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Formula C24H30ClN3O2
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Color White to off-white
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SMILES
O=C1C=CC2=C(N1)C=C(OCCCN3CCN(CC3)C4=CC=CC(C)=C4C)C=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (116.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: Lactic acid buffer (50 mM, pH 4.0)
Solubility: 4.3 mg/mL (10.05 mM); Clear solution; Need ultrasonic
Add each solvent one by one: Lactated Ringers solution
Solubility: 4.3 mg/mL (10.05 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3366 mL | 11.6831 mL | 23.3661 mL | 58.4153 mL |
| 5 mM | 0.4673 mL | 2.3366 mL | 4.6732 mL | 11.6831 mL | |
| 10 mM | 0.2337 mL | 1.1683 mL | 2.3366 mL | 5.8415 mL | |
| 15 mM | 0.1558 mL | 0.7789 mL | 1.5577 mL | 3.8944 mL | |
| 20 mM | 0.1168 mL | 0.5842 mL | 1.1683 mL | 2.9208 mL | |
| 25 mM | 0.0935 mL | 0.4673 mL | 0.9346 mL | 2.3366 mL | |
| 30 mM | 0.0779 mL | 0.3894 mL | 0.7789 mL | 1.9472 mL | |
| 40 mM | 0.0584 mL | 0.2921 mL | 0.5842 mL | 1.4604 mL | |
| 50 mM | 0.0467 mL | 0.2337 mL | 0.4673 mL | 1.1683 mL | |
| 60 mM | 0.0389 mL | 0.1947 mL | 0.3894 mL | 0.9736 mL | |
| 80 mM | 0.0292 mL | 0.1460 mL | 0.2921 mL | 0.7302 mL | |
| 100 mM | 0.0234 mL | 0.1168 mL | 0.2337 mL | 0.5842 mL |