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Cat. No.: HY-152951

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Palmostatin M

Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC₅₀ of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research.

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CAS No.: 1351669-68-5
화학식: C₂₂H₄₃NO₄S
분자량:417.65

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Palmostatin M Chemical Structure

CAS No.: 1351669-68-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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Biological Activity

제품 설명

All Ras Isoforms :

In Vitro

Palmostatin M potently inhibits recombinant human APT1 in a biochemical assay with an IC₅₀ of 2.5 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1351669-68-5
분자량 417.65
화학식 C₂₂H₄₃NO₄S
SMILES

C(CCCS(CCCN(C)C)(=O)=O)[C@H]1[C@H](CCCCCCCCCC)C(=O)O1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Rusch M, et al. Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M. Angew Chem Int Ed Engl. 2011;50(42):9838-9842. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Palmostatin M

All Ras Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Palmostatin M Related Classifications

HY-152951 Related Classifications