JAM-B/CD322
JAM-B (CD322) is the second member of the junctional adhesion molecule family and is distinguished from JAM-A by its highly restricted expression: it sits in the tight junctions of high endothelial venules of peripheral lymph nodes and of specialized epithelial barriers. Its best-characterized partner is JAM-C, with which it engages heterophilically across cell junctions, and interactions with integrins have also been described. Through these contacts JAM-B contributes to lymphocyte trafficking from blood into lymphoid tissue and to the structural organization of the venular wall. Because it marks high endothelial venules, recombinant JAM-B is used to study lymphocyte homing and the endothelial biology of secondary lymphoid organs.
-
JAM-B/CD322 Recombinant Proteins (5)
- Species:
- Source:
- Species:
- Source:
- Species:
- Source:
- Species:
- Source:
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
