country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-178248

Copy Link Print Information

PSMA-R2

PSMA ligand 2 is a prostate specific membrane antigen (PSMA) ligand with a glutamate-urea-lysine (GUL) moiety. PSMA ligand 2 can be efficiently labeled with radioactive nuclides such as ⁶⁸Ga and ¹⁷⁷Lu and specifically binds to PSMA-positive tumor cells. PSMA ligand 2 can be used for imaging of PSMA-expressing tumors or cells via PET or SPECT imaging. PSMA ligand 2 can be used for the research of prostate cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2576410-20-1
화학식: C₄₁H₆₃BrN₈O₁₅
분자량:987.89

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PSMA-R2 Chemical Structure

CAS No.: 2576410-20-1

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

PSMA ligand 2 (Compound PSMA‑R2) (10 μg/mL; 30-120 min) exhibits good stability in human plasma, with 85% recovery remaining after 2 hours of incubation at 37°C and 10 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

PSMA ligand 2 (⁶⁸Ga‑PSMA‑R2) (4.44-5.55 MBq; i.v.; single dose) exhibits renal excretion in healthy CD-1 mice, with high initial bladder uptake and decreasing kidney and systemic organ uptake over 4 hours post-injection^[1].
PSMA ligand 2 (68Ga‑PSMA‑R2) (4.5 MBq; i.v.; single dose) exhibits high uptake in PSMA-positive prostate tumors in athymic nude mice at 1 hour post-injection, with a tumor-to-kidney ratio of 5^[1].
PSMA ligand 2 (111 MBq; i.v.; single dose) significantly reduces PSMA-positive prostate tumor volumes in athymic nude mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mice bearing PC3-PIP^[1]
Dosage:

111 MBq
Administration:

i.v.; single dose
Result:

Reduced tumor volume.

Chemical Information

CAS No. 2576410-20-1
분자량 987.89
화학식 C₄₁H₆₃BrN₈O₁₅
SMILES

OC(CC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCCCN(C(CCCCCNC(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)CC2=CC=C(C=C2)Br)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Maurizio F. MARIANI, et al. Prostate specific membrane antigen (psma) ligands and uses thereof. WO2021001360A1. 2022-01-02

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기