QH536
QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research.
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- CAS No.: 2754254-07-2
- 화학식: C33H49N3O3
- 분자량:535.76
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
IC50: 0.22 μM (HMGCR)[1]
Chemical Information
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CAS No. 2754254-07-2
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분자량 535.76
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화학식 C33H49N3O3
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SMILES
C[C@@](C1=CC2)(CC(C=NN3C(C)=O)=C3C(C)1C)[C@](CC4)([H])[C@]2([H])[C@@](CC[C@]5([H])[C@H](C)CCC(N6CCOCC6)=O)([H])[C@]45C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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