SMM-189
SMM-189 is a potent and selective cannabinoid receptor 2 (CB2) inverse agonist. SMM-189 plays an important role in neurodegenerative disorders and traumatic brain injury research.
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- CAS No.: 1054451-07-8
- 화학식: C19H12Cl2O3
- 분자량:359.20
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
제품 설명
IC50 & Target
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CB2 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
153 nM
Compound: SMM-189
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Inverse agonist activity at CB2 receptor (unknown origin) expressed in HEK cells assessed as increase in cAMP production measured at 50 mins by ACTOne dye-based fluorescence assay in presence of forskolin and Ro 20-1724
Inverse agonist activity at CB2 receptor (unknown origin) expressed in HEK cells assessed as increase in cAMP production measured at 50 mins by ACTOne dye-based fluorescence assay in presence of forskolin and Ro 20-1724
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[PMID: 26275680] |
Chemical Information
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CAS No. 1054451-07-8
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분자량 359.20
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화학식 C19H12Cl2O3
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SMILES
O=C(C1=CC(O)=C(C2=CC(Cl)=CC(Cl)=C2)C(O)=C1)C3=CC=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SMM-189 Related Classifications
HY-100778 Related Classifications
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