Sordarin
Sordarin (Compound 1) is an antifungal agent targeting Elongation factor 2 (EF2) with a tetracyclic diterpene core including a norbornene system. Sordarin can be isolated from the fungus Sordaria araneosa. Sordarin has potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. Sordarin prevents the translocation of the ribosome along mRNA during elongation of the emerging polypeptide chain, inhibiting protein synthesis in fungi by stabilizing the ribosome/EF2 complex.
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- CAS No.: 11076-17-8
- 화학식: C27H40O8
- 분자량:492.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 11076-17-8
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분자량 492.60
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화학식 C27H40O8
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SMILES
OC([C@@]1([C@@]([C@@]2([H])[C@]([C@@H](CC2)C)([H])C3)(C4)C=O)[C@]3([C@@]4([H])C=C1C(C)C)CO[C@@H]5O[C@@H]([C@H]([C@H]([C@@H]5O)O)OC)C)=O
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Structure Classification
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Initial Source
Sordaria araneosa
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sordarin Related Classifications
HY-128478 Related Classifications
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