TOP5300
TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats.
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- CAS No.: 1848981-48-5
- 화학식: C28H29Cl2N5O4
- 분자량:570.47
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Biological Activity
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Biological Activity
Absorption, Distribution, Metabolism and Excretion (ADME) properties of TOP5300[1]
| Species | Dose (mg/kg) | AUCINF_obs (ng·h/mL) | t1/2 (h) | Cmax (ng/mL) | F (%) |
| Rat | 10 | 2655 | 5.1 | 237 | 20 |
| Mouse | 5 | 5533 | 2.5 | 1133 | 22 |
| Dog | 10 | 8719 | 391 | 32 |