Yhhu6669
Yhhu6669 is an anti-HBV agent. Yhhu6669 inhibits HBV DNA. Yhhu6669 inhibits HBV replication by inducing the formation of DNA-free capsids. Yhhu6669 decreases HBV DNA and HBcAg in AAV/HBV-infected mice. Yhhu6669 has favorable PK properties.
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- CAS No.: 2569526-80-1
- 화학식: C29H28ClFN6O3
- 분자량:563.02
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
63.12 μM
Compound: Yhhu6669; M0
|
Cytotoxicity against human HepG2.2.15 cells harboring HBV genome incubated for 8 days by MTT assay
Cytotoxicity against human HepG2.2.15 cells harboring HBV genome incubated for 8 days by MTT assay
|
[PMID: 37229833] |
Chemical Information
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CAS No. 2569526-80-1
-
분자량 563.02
-
화학식 C29H28ClFN6O3
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SMILES
ClC1=C(NCCCOC([C@@H](N)C(C)C)=O)N=C(F)C(C(C2=C3C=CC=C2)=NN(CC4=CC=C(C#N)C=C4)C3=O)=C1
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)