2. Others PI3K/Akt/mTOR Metabolic Enzyme/Protease Immunology/Inflammation Anti-infection
  3. Akt Arginase Bacterial Isotope-Labeled Compounds
  4. L-Valine-15N

L-Valine-15N ((S)-Valine-15N) is the 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.

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L-Valine-<sup>15</sup>N

L-Valine-15N Estructura química

No. CAS : 59935-29-4

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Other Forms of L-Valine-15N:

L-Valine-15N Related Antibodies

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Descripciòn

L-Valine-15N ((S)-Valine-15N) is the 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Valine-15N Related Antibodies
Peso molecular

118.14

Fòrmula

C5H1115NO2
No. CAS
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

CC(C)[C@H]([15NH2])C(O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvente y solubilidad
In Vitro: 

H2O : 20 mg/mL (169.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.4645 mL 42.3227 mL 84.6453 mL
5 mM 1.6929 mL 8.4645 mL 16.9291 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 99.74%

SDS (252 KB)

COA (248 KB) RP-HPLC (248 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.4645 mL 42.3227 mL 84.6453 mL 211.6133 mL
5 mM 1.6929 mL 8.4645 mL 16.9291 mL 42.3227 mL
10 mM 0.8465 mL 4.2323 mL 8.4645 mL 21.1613 mL
15 mM 0.5643 mL 2.8215 mL 5.6430 mL 14.1076 mL
20 mM 0.4232 mL 2.1161 mL 4.2323 mL 10.5807 mL
25 mM 0.3386 mL 1.6929 mL 3.3858 mL 8.4645 mL
30 mM 0.2822 mL 1.4108 mL 2.8215 mL 7.0538 mL
40 mM 0.2116 mL 1.0581 mL 2.1161 mL 5.2903 mL
50 mM 0.1693 mL 0.8465 mL 1.6929 mL 4.2323 mL
60 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5269 mL
80 mM 0.1058 mL 0.5290 mL 1.0581 mL 2.6452 mL
100 mM 0.0846 mL 0.4232 mL 0.8465 mL 2.1161 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Valine-15N Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Valine-15N59935-29-4(S)-Valine-15NAktArginaseBacterialIsotope-Labeled CompoundsPKBProtein kinase BInhibitorinhibitorinhibit

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Nombre del producto:
L-Valine-15N
Cat. No.:
HY-N0717S
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