2. Anti-infection
  3. Arenavirus
  4. LASV inhibitor 3.3

LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research.

For research use only. We do not sell to patients.

LASV inhibitor 3.3 Chemical Structure

LASV inhibitor 3.3 Chemical Structure

CAS No. : 554438-52-7

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5 mg USD 108 In-stock
10 mg USD 175 In-stock
25 mg USD 365 In-stock
50 mg USD 584 In-stock
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Based on 1 publication(s) in Google Scholar

LASV inhibitor 3.3 Related Antibodies

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Description

LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research[1].

In Vitro

LASV inhibitor 3.3 (1 nM-100 μM; 1 h) inhibits transduction by murine leukemia virus (MLV) pseudotyped with the indicated viral glycoproteins with an IC50 value of 1.8 μM[1].
LASV inhibitor 3.3 (1 and 10 μM; 1 h) inhibits LAMP1 binding to LASV GP in vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LASV inhibitor 3.3 Related Antibodies

Western Blot Analysis[1]

Cell Line: 293T LAMP1 KO cells expressing LASV GP-His and 293T pX459 cells
Concentration: 1 and 10 μM
Incubation Time: 1 hour
Result: Inhibited the LASV GP binds to LAMP1.
Molecular Weight

471.63

Formula

C30H37N3O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)NCC(N(CC4)CCN4C(C5=CC=CC=C5)C6=CC=CC=C6)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (53.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1203 mL 10.6015 mL 21.2031 mL
5 mM 0.4241 mL 2.1203 mL 4.2406 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1203 mL 10.6015 mL 21.2031 mL 53.0077 mL
5 mM 0.4241 mL 2.1203 mL 4.2406 mL 10.6015 mL
10 mM 0.2120 mL 1.0602 mL 2.1203 mL 5.3008 mL
15 mM 0.1414 mL 0.7068 mL 1.4135 mL 3.5338 mL
20 mM 0.1060 mL 0.5301 mL 1.0602 mL 2.6504 mL
25 mM 0.0848 mL 0.4241 mL 0.8481 mL 2.1203 mL
30 mM 0.0707 mL 0.3534 mL 0.7068 mL 1.7669 mL
40 mM 0.0530 mL 0.2650 mL 0.5301 mL 1.3252 mL
50 mM 0.0424 mL 0.2120 mL 0.4241 mL 1.0602 mL
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LASV inhibitor 3.3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LASV inhibitor 3.3554438-52-7Arenavirusglycoproteinmembrane fusioninfectionMLVInhibitorinhibitorinhibit

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