Bile Acids

Tauro-3α,6α,7α,12α-tetrahydroxy bile acid sodium is a type of bile acid, belonging to biomolecules synthesized by the liver using cholesterol as a raw material. Bile acids play a critical role in the digestion and absorption of lipids in the small intestine.

Cholyl-L-lysine fluorescein disodium is a Fluorescent substrate. Cholyl-L-lysine fluorescein disodium can be used in organoid research.

3?-Hydroxy-7-oxo-5-cholestenoic acid is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

3a,6a-Dihydroxy-7-oxo-5b-cholan-24-oic acid is an ester product.

4-Cholenic acid-3-one is an antifeedant steroid metabolite formed via anaerobic biotransformation of Lithocholic acid (HY-B0172) by Pseudomonas sp. strain NCIB 10590.

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid (HDCA).

3β,25-OH-7-Oxo-5-cholestenoic acid is an oxysterol.

3β,5α,6β-Trihydroxycholanic acid is a metabolite of 3β,5α,6β-Trihydroxycholestane (HY-W010934). 3β,5α,6β-Trihydroxycholanic acid can be used in research related to neurodegenerative diseases associated with lysosomal dysfunction.

(3β)-3-Hydroxy-7-oxochol-5-en-24-oic acid is a bile acid, and is a metabolite of 7β-hydroxy cholesterol (HY-113341).

7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) serves as a ligand for liver X receptor (LXR), binding specifically to the ligand binding domains of both LXRα and LXRβ. This compound is synthetically produced from E-α,β-enone, utilizing Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde as starting materials, followed by a series of transformations to yield 7α,24(S)-dihydroxycholesterol.

Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant.

Chenodeoxycholic acid 7-sulfate sodium, a bile acid, is a metabolite of Chenodeoxycholic acid (HY-76847).

Glycoursodeoxycholic acid 3-sulfate is a glycine-conjugated sulfated bile acid 3-sulfate, which is produced by SULT2A1-mediated sulfation of glycoursodeoxycholic acid (HY-N1424) in the liver. Glycoursodeoxycholic acid 3-sulfate attenuates the anti-inflammatory effect of glycoursodeoxycholic acid and impairs the inhibitory effect on the IL-17 and NF-κB signaling pathways. Glycoursodeoxycholic acid 3-sulfate shows a significant correlation with aortic flow velocity and BNP in patients with aortic stenosis. Glycoursodeoxycholic acid 3-sulfate is mainly used in related studies such as quantitative analysis, quality control and biochemical experiments; it often serves as a reagent for metabolomics analysis and can also be applied to research related to aortic stenosis.

5β-Cholestane-3α,7α,12α,25,27-pentol is a bile alcohol found in amphibian bile. 5β-Cholestane-3α,7α,12α,25,27-pentol serves as a principal or sole constituent of sulfate-conjugated bile salts in gallbladder bile of the caecilian Dermophis mexicanus. 5β-Cholestane-3α,7α,12α,25,27-pentol appears as a minor constituent in bile of the toad Bufo b. formosus. 5β-Cholestane-3α,7α,12α,25,27-pentol may represent the end product of cholesterol metabolism in the caecilian, as bile acids remain undetected in this organism.

(7α,24S)-7,24-Dihydroxycholest-4-en-3-one is an oxysterol.

3-Oxo-4-cholestenoic acid is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

Chenodeoxycholyl-putrescine is a polyamine bile amidate.

Cholyl-1,3-diaminopropane is a polyamine bile amidate.

Cholyl-putrescine is a polyamine bile amidate.

Cholyl-cadaverine is a polyamine bile amidate.