Polyketides

Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6).

6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC₅₀ values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent.

4'-Methoxypuerarin (4'-O-Methylpuerarin), an isoflavone diglycoside, is isolated from Pueraria lobata.

Myrigalone A (MyA) is a plant ethylene biosynthesis inhibitor and natural herbicide. Myrigalone A possesses antioxidant, antifungal, and antimicrobial activities. Myrigalone A interferes with auxin homeostasis during seed germination. Myrigalone A delays seed germination, inhibits the formation of roots, hypocotyls, and root hairs, and causes developmental delay in specific organisms. Myrigalone A triggers the induction of detoxification programs, alters the metabolism of gibberellins, cis-(+)-12-oxophytodienoic acid, and jasmonic acid, disrupts the antioxidant system and oxidative signaling, and impairs the function of aquaporins and water uptake in imbibed seeds. Myrigalone A can be used in studies related to herbicides and plant growth regulators.

6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin) is a potent BCRP/ABCG2 inhibitor (IC₅₀ = 0.410 μM) and a non-competitive allosteric PTP1B inhibitor (IC₅₀ = 1.04 μM; K_i = 1.56 μM) that is isolated from Humulus lupulus. 6,8-Diprenylnaringenin produces non-competitive allosteric inhibition by locking the WPD catalytic loop of PTP1B in an inactive open conformation, while simultaneously binding to and inhibiting the ABCG2 drug efflux pump. 6,8-Diprenylnaringenin also exhibits antibacterial activity against MRSA (MIC = 6-13 μM) and antioxidant activity. 6,8-Diprenylnaringenin is used in research on type 2 diabetes, obesity, MRSA infection, and atherosclerosis.

2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC₅₀ of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties.

Sanggenol O is an active product that can be extracted from Morus alba. Sanggenol O has hepatoprotective and neuroprotective activities with EC₅₀s more than 80 μM in HepG2 and HT22 cells.

Kaempferol-7-O-β-D-galactopyranoside is a flavonoid glycoside found in the aerial parts of Gynostemma pentaphyllum with no significant antiproliferative activity against cancer cells.

Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities.

Quercetin 4′-O-D-galactoside (Quercetin 4′-O-β-galactopyranoside) is a natural product.

Linaroside is a flavonoid, that can be isolated from Lantana camara.

Parvifuran is a Phenols product that can be isolated from the heartwoods of Dalbergia parviflora..

Syringetin 3-O-galactoside is a Flavonoids product that can be isolated from the leaves of Corylus heterophylla Fisch.

Daidzein-4'-glucoside is a Flavonoids product that can be isolated from the fruits of Sophora japonica L..

Vitexin 2''-O-(4'''-O-acetyl)rhamnoside (4'''-O-Acetyl-2''-O-rhamnosylvitexin) is a Diterpenoids product that can be isolated from the needles and twigs of Taxus cuspidata..

Dihydropedicin is a Chalcones product that can be isolated from the herbs of Fissistigma lanuginosum.

5,6,7,4'-Tetrahydroxyflavonol 3-O-rutinoside is a natural antioxidant flavonoid glycoside.

4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC₅₀50 of 15 μM.

Syringetin-3-O-rutinoside is an antioxidant compound. Syringetin-3-O-rutinoside can be used for the synthesis of syringetin-O-glycoside derivatives.