M4R ligand-1
M4R ligand-1 is a M4R ligand. M4R ligand-1 binds to the extracellular vestibular allosteric site of M4R. M4R ligand-1 can be used for the research of schizophrenia.
For research use only. We do not sell to patients.
- Formula: C24H24N4O3
- Molecular Weight:416.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
mAChR4 |
In Vitro
M4R ligand-1 (MKcpd-97(2)) is a positive allosteric modulator of M4R; when combined with ACh, its allosteric site affinity pKB is 6.50; when combined with Xanomeline (HY-105182), the corresponding allosteric site affinity pKB is 6.14[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Molecular Weight 416.47
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Formula C24H24N4O3
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SMILES
CN1C(C2=CC(C3=NC(C(O)=O)=CC=C3C4=CN(N=C4)CC5CCCC5)=CC=C2C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M4R ligand-1 Related Classifications
HY-189040 Related Classifications
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