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Cat. No.: HY-137750

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MANT-cGMP

MANT-cGMP, a ribose-substituted nucleotide, is an adenylyl cyclase (AC) inhibitor with a K_i of 100 μM and a pK_i of 4. MANT-cGMP can be used for the study of heart failure, cancer, and neurological disorders.

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CAS No.: 83707-15-7
Formule: C₁₈H₁₉N₆O₈P
Masse moléculaire:478.35

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

MANT-cGMP Chemical Structure

CAS No.: 83707-15-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-137016A
8-Pcpt-cGMP sodium

CNG Channel Agonist

Activité biologique

Description

Chemical Information

CAS No. 83707-15-7
Masse moléculaire 478.35
Formule C₁₈H₁₉N₆O₈P
SMILES

O=C(C(C=CC=C1)=C1NC)O[C@H]2[C@@](N3C(NC(N)=NC4=O)=C4N=C3)([H])O[C@@](CO5)([H])[C@@]2([H])O[P]5(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang JL, et al. A conformational transition in the adenylyl cyclase catalytic site yields different binding modes for ribosyl-modified and unmodified nucleotide inhibitors. Bioorg Med Chem. 2007 Apr 15;15(8):2993-3002. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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