Bleximenib (Synonyms: Menin-MLL inhibitor 24)

Cat. No.: HY-148669: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Bleximenib (Menin-MLL inhibitor 24) (compound A) is a menin-mixed-lineage leukemia 1 (menin-MLL) inhibitor. Bleximenib can be used for the research of cancer.

For research use only. We do not sell to patients.

Bleximenib Chemical Structure

CAS No. : 2654081-35-1

Size		Stock
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Bleximenib:

Bleximenib oxalate (S)-Bleximenib oxalate

Other Forms of Bleximenib:

Bleximenib oxalate In-stock
(S)-Bleximenib oxalate In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Bleximenib (Menin-MLL inhibitor 24) (compound A) is a menin-mixed-lineage leukemia 1 (menin-MLL) inhibitor. Bleximenib can be used for the research of cancer^[1].

Molecular Weight

599.78

Formula

C₃₂H₅₀FN₇O₃

CAS No.

2654081-35-1

SMILES

COCCN(C)CCC[C@@H](N1CC2(C1)CN(C3=NC=NN=C3OC4=C(C=C(C=C4)F)C(N(CC)C(C)C)=O)CC2)C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (166.73 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6673 mL	8.3364 mL	16.6728 mL
5 mM	0.3335 mL	1.6673 mL	3.3346 mL
10 mM	0.1667 mL	0.8336 mL	1.6673 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. DASKALAKIS N, et, al. Combination therapies. WO2022237720A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6673 mL	8.3364 mL	16.6728 mL	41.6819 mL
	5 mM	0.3335 mL	1.6673 mL	3.3346 mL	8.3364 mL
	10 mM	0.1667 mL	0.8336 mL	1.6673 mL	4.1682 mL
	15 mM	0.1112 mL	0.5558 mL	1.1115 mL	2.7788 mL
	20 mM	0.0834 mL	0.4168 mL	0.8336 mL	2.0841 mL
	25 mM	0.0667 mL	0.3335 mL	0.6669 mL	1.6673 mL
	30 mM	0.0556 mL	0.2779 mL	0.5558 mL	1.3894 mL
	40 mM	0.0417 mL	0.2084 mL	0.4168 mL	1.0420 mL
	50 mM	0.0333 mL	0.1667 mL	0.3335 mL	0.8336 mL
	60 mM	0.0278 mL	0.1389 mL	0.2779 mL	0.6947 mL
	80 mM	0.0208 mL	0.1042 mL	0.2084 mL	0.5210 mL
	100 mM	0.0167 mL	0.0834 mL	0.1667 mL	0.4168 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Bleximenib Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bleximenib2654081-35-1Menin-MLL inhibitor 24Epigenetic Reader DomainInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks