Meranzin hydrate (Standard)
Meranzin hydrate (Standard) is the analytical standard of Meranzin hydrate (HY-N3297). This product is intended for research and analytical applications. Meranzin hydrate is an orally active antidepressant and GHSR modulator. Meranzin hydrate significantly upregulates the expression levels of brain-derived neurotrophic factor and p-mTOR in the hippocampus via the ghrelin-growth hormone secretagogue receptor pathway. Meranzin hydrate regulates blood oxygen level-dependent signals in the hippocampus-thalamus-basal ganglia circuit, attenuates reward system activation, and promotes the normalization of related hormone levels. Meranzin hydrate effectively ameliorates depression-like behaviors and gastrointestinal hypomotility, and can be used in research related to depression and major depressive disorder.
For research use only. We do not sell to patients.
- CAS No.: 5875-49-0
- Formula: C15H18O5
- Molecular Weight:278.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 5875-49-0
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Molecular Weight 278.30
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Formula C15H18O5
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SMILES
CC(C)(O)[C@@H](O)CC1=C(O2)C(C=CC2=O)=CC=C1OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Liu YL, et al. Meranzin Hydrate Improves Depression-Like Behaviors and Hypomotility via Ghrelin and Neurocircuitry. Chinese journal of integrative medicine. 2023 Jun;29(6):490-499. [Content Brief]
[2]. Liu X, et al. Meranzin hydrate elicits antidepressant effects and restores reward circuitry. Behavioural brain research. 2021 Feb 01;398:112898. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Meranzin hydrate (Standard)
- 5875-49-0
- Reference Standards
- mTOR
- GHSR
- GHSR KO mice
- acylated ghrelin
- wild-type mice
- adrenocorticotropic hormone
- Aurantii Fructus Immaturus
- corticosterone
- brain-derived neurotrophic factor
- phosphorylated mammalian target of rapamycin
- ghrelin-growth hormone secretagogue receptor pathway
- hippocampus-thalamus-basal ganglia
- Inhibitor
- inhibitor
- inhibit