Metallo β-lactamase ligand 1
Based on 1 Customer Validation
Metallo-beta-lactamase ligand 1 is a class B β-lactamase inhibitor with antibacterial activity extracted from patent WO2019221122A1, compound A.
For research use only. We do not sell to patients.
- Purity: 99.23%
- CAS No.: 1087784-71-1
- Formula: C7H9NO5S
- Molecular Weight:219.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
One effective measure against β-lactam antibacterial resistant bacteria is to use an inhibitor of β-lactamase, the enzyme responsible for its resistance mechanism, together with an appropriate β-lactam antibacterial agent[1].
The toxicity of Metallo-beta-lactamase ligand 1 (Compound A) is extremely low in HeLa cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1087784-71-1
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Appearance Solid
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Molecular Weight 219.22
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Formula C7H9NO5S
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Color Light yellow to light brown
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SMILES
CC1=C(S(=O)(N)=O)C(C(O)=O)=C(C)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (1140.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5616 mL | 22.8081 mL | 45.6163 mL | 114.0407 mL |
| 5 mM | 0.9123 mL | 4.5616 mL | 9.1233 mL | 22.8081 mL | |
| 10 mM | 0.4562 mL | 2.2808 mL | 4.5616 mL | 11.4041 mL | |
| 15 mM | 0.3041 mL | 1.5205 mL | 3.0411 mL | 7.6027 mL | |
| 20 mM | 0.2281 mL | 1.1404 mL | 2.2808 mL | 5.7020 mL | |
| 25 mM | 0.1825 mL | 0.9123 mL | 1.8247 mL | 4.5616 mL | |
| 30 mM | 0.1521 mL | 0.7603 mL | 1.5205 mL | 3.8014 mL | |
| 40 mM | 0.1140 mL | 0.5702 mL | 1.1404 mL | 2.8510 mL | |
| 50 mM | 0.0912 mL | 0.4562 mL | 0.9123 mL | 2.2808 mL | |
| 60 mM | 0.0760 mL | 0.3801 mL | 0.7603 mL | 1.9007 mL | |
| 80 mM | 0.0570 mL | 0.2851 mL | 0.5702 mL | 1.4255 mL | |
| 100 mM | 0.0456 mL | 0.2281 mL | 0.4562 mL | 1.1404 mL |
Metallo β-lactamase ligand 1 Related Classifications
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