MMPIP hydrochloride (Standard)
MMPIP hydrochloride (Standard) is the analytical standard of MMPIP hydrochloride (HY-103111). This product is intended for research and analytical applications. MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice.
For research use only. We do not sell to patients.
- CAS No.: 1215566-78-1
- Formula: C19H16ClN3O3
- Molecular Weight:369.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1215566-78-1
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Molecular Weight 369.80
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Formula C19H16ClN3O3
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SMILES
O=C1C2=C(ON=C2C3=CC=NC=C3)C=C(C4=CC=C(OC)C=C4)N1C.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gentaroh Suzuki, et al. In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists. J Pharmacol Exp Ther. 2007 Oct;323(1):147-56. [Content Brief]
[2]. Paulina Cieślik, et al. Negative Allosteric Modulators of mGlu 7 Receptor as Putative Antipsychotic Drugs. Front Mol Neurosci. 2018 Sep 20;11:316. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)