Monobutyl phthalate-d₄

Name: Monobutyl phthalate-d 4
Brand: MedChemExpress
SKU: HY-N7143S
Rating: 4.5 (0 reviews)

Cat. No.: HY-N7143S Purity: 98.43%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Monobutyl phthalate-d₄ is the deuterium labeled Monobutyl phthalate. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant.

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Monobutyl phthalate-d₄ 화학구조

CAS No. : 478954-81-3

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Monobutyl phthalate-d₄:

Monobutyl phthalate In-stock

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•Related Small Molecules:

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Monobutyl phthalate-d₄ is the deuterium labeled Monobutyl phthalate^[1]. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant^[2]^[3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

226.26

화학식

C₁₂H₁₀D₄O₄

CAS No.

478954-81-3

Unlabeled CAS

131-70-4

Appearance

Solid

Color

White to off-white

SMILES

CCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (441.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4197 mL	22.0985 mL	44.1969 mL
5 mM	0.8839 mL	4.4197 mL	8.8394 mL
10 mM	0.4420 mL	2.2098 mL	4.4197 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.33%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (249 KB) HNMR (335 KB) RP-HPLC (728 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. van Dartel DA, et al. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod Toxicol. 2009 Apr;27(2):93-102. [Content Brief]

[3]. Ema M, et al. Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats. Congenit Anom (Kyoto). 2002 Dec;42(4):297-308. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4197 mL	22.0985 mL	44.1969 mL	110.4924 mL
	5 mM	0.8839 mL	4.4197 mL	8.8394 mL	22.0985 mL
	10 mM	0.4420 mL	2.2098 mL	4.4197 mL	11.0492 mL
	15 mM	0.2946 mL	1.4732 mL	2.9465 mL	7.3662 mL
	20 mM	0.2210 mL	1.1049 mL	2.2098 mL	5.5246 mL
	25 mM	0.1768 mL	0.8839 mL	1.7679 mL	4.4197 mL
	30 mM	0.1473 mL	0.7366 mL	1.4732 mL	3.6831 mL
	40 mM	0.1105 mL	0.5525 mL	1.1049 mL	2.7623 mL
	50 mM	0.0884 mL	0.4420 mL	0.8839 mL	2.2098 mL
	60 mM	0.0737 mL	0.3683 mL	0.7366 mL	1.8415 mL
	80 mM	0.0552 mL	0.2762 mL	0.5525 mL	1.3812 mL
	100 mM	0.0442 mL	0.2210 mL	0.4420 mL	1.1049 mL