Mosapride citrate (Standard)
Mosapride (citrate) (Standard) is the analytical standard of Mosapride (citrate). This product is intended for research and analytical applications. Mosapride citrate is an orally active gastroenterokinetic compound. Mosapride citrate is a 5HT4 agonist. Mosapride citrate is a CYP inducer. Mosapride citrate has a concentration-dependent inhibitory effect on Kv4.3, and its IC50 value is 15.2 μM. Mosapride citrate can be used in the study of gastrointestinal diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98%
- CAS No.: 112885-42-4
- Formule: C27H33ClFN3O10
- Masse moléculaire:614.02
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureté et documentation
-
Help & FAQs
-
HY-B0189A
Mosapride citrate5HT4 Agonist -
HY-14149
Cisapride5-HT4 Receptor Agonist/hERG Potassium Channel blocker -
HY-B0121B
Sumatriptan5-HT1 Receptor Agonist -
HY-14542
Ziprasidone5-HT/DA Receptor Antagonist -
HY-14153A
Tegaserod maleateSerotonin Receptor 4 Agonist -
HY-14153
TegaserodSerotonin Receptor 4 Agonist -
HY-15419
RS-127445 hydrochloride5-HT2B Antagonist -
HY-B0229
Zolmitriptan5-HT1B/1D Agonist -
HY-B1115
Buspirone hydrochloride5-HT1A Receptor Agonist -
HY-B0189
Mosapride5HT4 Agonist -
HY-A0010
Eletriptan hydrobromide5-HT1B/D Receptor Agonist -
HY-B0206
Rizatriptan benzoate5-HT1 Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 112885-42-4
-
Masse moléculaire 614.02
-
Formule C27H33ClFN3O10
-
SMILES
O=C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)C3=CC(Cl)=C(N)C=C3OCC.O=C(CC(C(O)=O)(O)CC(O)=O)O
-
Synonyms
TAK-370 citrate (Standard); AS-4370 citrate (Standard)
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67. [Content Brief]
[2]. Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91. [Content Brief]
[3]. Kim HS, et al. The effect of mosapride citrate on proximal and distal colonic motor function in the guinea-pig in vitro. Neurogastroenterol Motil. 2008 Feb;20(2):169-76. [Content Brief]
[4]. Kim YH, et al. Measurement of Human Cytochrome P450 Enzyme Induction Based on Mesalazine and Mosapride Citrate Treatments Using a Luminescent Assay. Biomol Ther (Seoul). 2015 Sep;23(5):486-92. [Content Brief]
[5]. Uchida M, et al. Dual role of mosapride citrate hydrate on the gastric emptying evaluated by the breath test in conscious rats. J Pharmacol Sci. 2013;121(4):282-7. [Content Brief]
[6]. Fujisawa M, et al. The 5-HT4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage. J Gastroenterol. 2010 Feb;45(2):179-86. [Content Brief]
[7]. Sung KW, et al. Effect of mosapride on Kv4.3 potassium channels expressed in CHO cells. Naunyn Schmiedebergs Arch Pharmacol. 2013 Oct;386(10):905-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mosapride citrate (Standard) Related Classifications
HY-B0189AR Related Classifications
Powered by Bioz
Keywords
- Mosapride citrate (Standard)
- 112885-42-4
- TAK-370 citrate (Standard)
- AS-4370 citrate (Standard)
- 5-HT Receptor
- Potassium Channel
- Cytochrome P450
- Reference Standards
- Serotonin Receptor
- 5-hydroxytryptamine Receptor
- KcsA
- CYPs
- 5-HT4
- Agonist
- CYP
- HMC424
- HMC478
- HMC493
- gastric emptying in rat
- gastrointestinal disease
- Inhibitor
- inhibitor
- inhibit