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Cat. No.: HY-164683

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MRP1-IN-1

Name: MRP1-IN-1
Brand: MedChemExpress
SKU: HY-164683
Price: 127.00 USD
Availability: InStock
Rating: 5 (1 reviews)

MRP1-IN-1 (Compound 9h) is a MRP1 inhibitor with an EC₅₀ of 0.90 μM in HeLa-T5 cells.

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CAS No.: 246238-55-1
화학식: C₂₈H₂₄ClN₃O₆
분자량:533.96

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

MRP1-IN-1 Chemical Structure

CAS No.: 246238-55-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

MRP1-IN-1 (Compound 9h) is a MRP1 inhibitor with an EC₅₀ of 0.90 μM in HeLa-T5 cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	1.8 μM Compound: LY-402913	Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation counting Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation counting	[PMID: 19580319]

Chemical Information

CAS No. 246238-55-1
분자량 533.96
화학식 C₂₈H₂₄ClN₃O₆
SMILES

O=C1C2=C(C)ON=C2C3=C(N1C4=CC=CC(CC(NC5=CC(OC)=C(C(OC)=C5)OC)=O)=C4)C=CC=C3Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Norman BH, et, al. Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1). Bioorg Med Chem Lett. 2002 Mar 25;12(6):883-6. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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