MRS 2179 ammonium

Cat. No.: HY-115273A Purity: 99.34%: Data Sheet
COA

SDS
Handling Instructions
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MRS 2179 ammonium is a selective and competitive antagonist for P2Y1 receptor, with K_B of 0.177 μM.

For research use only. We do not sell to patients.

MRS 2179 ammonium Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Biological Activity
Purity & Documentation
References
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Description

MRS 2179 ammonium is a selective and competitive antagonist for P2Y1 receptor, with K_B of 0.177 μM^[1].

Molecular Weight

493.35

Formula

C₁₁H₂₉N₉O₉P₂

Appearance

Crystal

Color

Colorless to light yellow

SMILES

OP(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC)=NC=N3)C[C@@H]1OP(O)(O)=O)(O)=O.N.N.N.N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 62.5 mg/mL (126.68 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0270 mL	10.1348 mL	20.2696 mL
5 mM	0.4054 mL	2.0270 mL	4.0539 mL
10 mM	0.2027 mL	1.0135 mL	2.0270 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (253 KB) HNMR (247 KB) CNMR (236 KB) LCMS (107 KB)

Handling Instructions (2659 KB)

References

[1]. Moro S, et al., Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites. J Med Chem. 1998 Apr 23;41(9):1456-66. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.0270 mL	10.1348 mL	20.2696 mL	50.6740 mL
	5 mM	0.4054 mL	2.0270 mL	4.0539 mL	10.1348 mL
	10 mM	0.2027 mL	1.0135 mL	2.0270 mL	5.0674 mL
	15 mM	0.1351 mL	0.6757 mL	1.3513 mL	3.3783 mL
	20 mM	0.1013 mL	0.5067 mL	1.0135 mL	2.5337 mL
	25 mM	0.0811 mL	0.4054 mL	0.8108 mL	2.0270 mL
	30 mM	0.0676 mL	0.3378 mL	0.6757 mL	1.6891 mL
	40 mM	0.0507 mL	0.2534 mL	0.5067 mL	1.2668 mL
	50 mM	0.0405 mL	0.2027 mL	0.4054 mL	1.0135 mL
	60 mM	0.0338 mL	0.1689 mL	0.3378 mL	0.8446 mL
	80 mM	0.0253 mL	0.1267 mL	0.2534 mL	0.6334 mL
	100 mM	0.0203 mL	0.1013 mL	0.2027 mL	0.5067 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.