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  3. Muvalaplin tetrahydrochloride

Muvalaplin tetrahydrochloride  (Synonyms: LY3473329 tetrahydrochloride)

Cat. No.: HY-46749 Pureza: 99.55%
Instrucciones de manejo Technical Support

Muvalaplin tetrahydrochloride (LY3473329) is an orally active reagent of lipoprotein (a) (Lp (a)). At present, research on Muvalaplin tetrahydrochloride oral reagent is ongoing.

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Muvalaplin tetrahydrochloride

Muvalaplin tetrahydrochloride Estructura química

No. CAS : 2565656-71-3

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
En stock
Solution
10 mM * 1 mL in Water En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Muvalaplin tetrahydrochloride:

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  • Actividad biológica

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Descripciòn

Muvalaplin tetrahydrochloride (LY3473329) is an orally active reagent of lipoprotein (a) (Lp (a)). At present, research on Muvalaplin tetrahydrochloride oral reagent is ongoing[1].

Peso molecular

856.75

Fòrmula

C42H58Cl4N4O6

No. CAS
Appearance

Solid

Color

White to off-white

SMILES

OC([C@H]([C@H]1CCNC1)CC2=CC(CN(CC3=CC(C[C@@H]([C@H]4CCNC4)C(O)=O)=CC=C3)CC5=CC(C[C@@H]([C@H]6CCNC6)C(O)=O)=CC=C5)=CC=C2)=O.[H]Cl.[H]Cl.[H]Cl.[H]Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : ≥ 100 mg/mL (116.72 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1672 mL 5.8360 mL 11.6720 mL
5 mM 0.2334 mL 1.1672 mL 2.3344 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1672 mL 5.8360 mL 11.6720 mL 29.1800 mL
5 mM 0.2334 mL 1.1672 mL 2.3344 mL 5.8360 mL
10 mM 0.1167 mL 0.5836 mL 1.1672 mL 2.9180 mL
15 mM 0.0778 mL 0.3891 mL 0.7781 mL 1.9453 mL
20 mM 0.0584 mL 0.2918 mL 0.5836 mL 1.4590 mL
25 mM 0.0467 mL 0.2334 mL 0.4669 mL 1.1672 mL
30 mM 0.0389 mL 0.1945 mL 0.3891 mL 0.9727 mL
40 mM 0.0292 mL 0.1459 mL 0.2918 mL 0.7295 mL
50 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5836 mL
60 mM 0.0195 mL 0.0973 mL 0.1945 mL 0.4863 mL
80 mM 0.0146 mL 0.0730 mL 0.1459 mL 0.3648 mL
100 mM 0.0117 mL 0.0584 mL 0.1167 mL 0.2918 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Muvalaplin tetrahydrochloride
Cat. No.:
HY-46749
Cantidad:
MCE Japan Authorized Agent: