Myoseverin B
Myoseverin B is a microtubule assembly inhibitor capable of inhibiting the polymerization of tubulin (IC50 = 2 μM) and exhibiting low cytotoxicity in most cell types. Myoseverin B can be used in research as an antitumor agent.
For research use only. We do not sell to patients.
- CAS No.: 361431-27-8
- Formula: C27H32N6O2
- Molecular Weight:472.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 2 μM (Tubulin)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | GI50 |
0.2 μM
Compound: 6
|
Growth inhibition of human U937 cells
Growth inhibition of human U937 cells
|
[PMID: 11741468] |
Chemical Information
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CAS No. 361431-27-8
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Molecular Weight 472.58
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Formula C27H32N6O2
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SMILES
COC1=CC=C(CNC2=C3N=CN(C4CCCCC4)C3=NC(NCC5=CC=C(OC)C=C5)=N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)