NDM-1 inhibitor-5
NDM-1 inhibitor-5 (compound 57) is a potent NDM-1 inhibitor, with a Ki of 2.5 μM. NDM-1 inhibitor-5 also shows antibacterial synergistic activity with meropenem (HY-13678).
For research use only. We do not sell to patients.
- CAS No.: 1613045-02-5
- Formula: C24H23NO4
- Molecular Weight:389.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK-II | IC50 |
10.5 μM
Compound: 3d
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Inhibition of ABCC2 (unknown origin) expressed in MDCK2 cells assessed as inhibition of calcein-AM efflux measured after 30 mins in presence of ABCB1 inhibitor GF120918 and ABCC1 inhibitor MK-571 by flow cytometry
Inhibition of ABCC2 (unknown origin) expressed in MDCK2 cells assessed as inhibition of calcein-AM efflux measured after 30 mins in presence of ABCB1 inhibitor GF120918 and ABCC1 inhibitor MK-571 by flow cytometry
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[PMID: 27393949] |
Chemical Information
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CAS No. 1613045-02-5
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Molecular Weight 389.44
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Formula C24H23NO4
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SMILES
O=C(/C(OC1=CC(O)=C2)=C/C3=CN(CC4CCCCC4)C5=CC=CC=C35)C1=C2O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NDM-1 inhibitor-5 Related Classifications
HY-163191 Related Classifications
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