Nifenalol hydrochloride
Based on 1 Customer Validation
Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 5704-60-9
- Formula: C11H17ClN2O3
- Molecular Weight:260.72
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Adrenergic Receptor Isoforms
More
Biological Activity
|
β-adrenoceptor |
Chemical Information
-
CAS No. 5704-60-9
-
Appearance Solid
-
Molecular Weight 260.72
-
Formula C11H17ClN2O3
-
Color White to off-white
-
SMILES
OC(CNC(C)C)C1=CC=C([N+]([O-])=O)C=C1.[H]Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 250 mg/mL (958.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 50 mg/mL (191.78 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.8355 mL | 19.1777 mL | 38.3553 mL | 95.8883 mL |
| 5 mM | 0.7671 mL | 3.8355 mL | 7.6711 mL | 19.1777 mL | |
| 10 mM | 0.3836 mL | 1.9178 mL | 3.8355 mL | 9.5888 mL | |
| 15 mM | 0.2557 mL | 1.2785 mL | 2.5570 mL | 6.3926 mL | |
| 20 mM | 0.1918 mL | 0.9589 mL | 1.9178 mL | 4.7944 mL | |
| 25 mM | 0.1534 mL | 0.7671 mL | 1.5342 mL | 3.8355 mL | |
| 30 mM | 0.1279 mL | 0.6393 mL | 1.2785 mL | 3.1963 mL | |
| 40 mM | 0.0959 mL | 0.4794 mL | 0.9589 mL | 2.3972 mL | |
| 50 mM | 0.0767 mL | 0.3836 mL | 0.7671 mL | 1.9178 mL | |
| 60 mM | 0.0639 mL | 0.3196 mL | 0.6393 mL | 1.5981 mL | |
| 80 mM | 0.0479 mL | 0.2397 mL | 0.4794 mL | 1.1986 mL | |
| 100 mM | 0.0384 mL | 0.1918 mL | 0.3836 mL | 0.9589 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.