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Cat. No.: HY-N12693

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Isobiflorin

Isobiflorin is an anti-inflammatory agent and can be isolated from Syzygium aromaticum. Isobiflorin inhibits LPS-induced PGE2 production with an IC₅₀ value of 46.0 μM.

For research use only. We do not sell to patients.

CAS No.: 152041-16-2
Formula: C₁₆H₁₈O₉
Molecular Weight:354.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Isobiflorin Chemical Structure

CAS No.: 152041-16-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isobiflorin is an anti-inflammatory agent and can be isolated from Syzygium aromaticum. Isobiflorin inhibits LPS-induced PGE2 production with an IC₅₀ value of 46.0 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>60 μM Compound: 2	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 1 hr followed by LPS challenge for 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 1 hr followed by LPS challenge for 24 hrs by Griess assay	[PMID: 26977531]
RAW264.7	IC₅₀	46 μM Compound: 2	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production preincubated for 1 hr followed by LPS challenge for 24 hrs by ELISA method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production preincubated for 1 hr followed by LPS challenge for 24 hrs by ELISA method	[PMID: 26977531]

Chemical Information

CAS No. 152041-16-2
Molecular Weight 354.31
Formula C₁₆H₁₈O₉
SMILES

OC1=CC(O)=C(C(C=C(O2)C)=O)C2=C1[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
Structure Classification
- Saccharides
- Monosaccharides
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee HH, et al. Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock. J Nat Prod. 2016 Apr 22;79(4):711-20. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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