UCCF-853
Based on 1 Customer Validation
UCCF-853 is a CFTR modulator.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 625458-06-2
- Formula: C14H8ClF3N2O
- Molecular Weight:312.67
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
-
CAS No. 625458-06-2
-
Appearance Solid
-
Molecular Weight 312.67
-
Formula C14H8ClF3N2O
-
Color White to off-white
-
SMILES
O=C1N(C2=CC=C(C=C2N1)C(F)(F)F)C3=CC=CC(Cl)=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 125 mg/mL (399.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1983 mL | 15.9913 mL | 31.9826 mL | 79.9565 mL |
| 5 mM | 0.6397 mL | 3.1983 mL | 6.3965 mL | 15.9913 mL | |
| 10 mM | 0.3198 mL | 1.5991 mL | 3.1983 mL | 7.9957 mL | |
| 15 mM | 0.2132 mL | 1.0661 mL | 2.1322 mL | 5.3304 mL | |
| 20 mM | 0.1599 mL | 0.7996 mL | 1.5991 mL | 3.9978 mL | |
| 25 mM | 0.1279 mL | 0.6397 mL | 1.2793 mL | 3.1983 mL | |
| 30 mM | 0.1066 mL | 0.5330 mL | 1.0661 mL | 2.6652 mL | |
| 40 mM | 0.0800 mL | 0.3998 mL | 0.7996 mL | 1.9989 mL | |
| 50 mM | 0.0640 mL | 0.3198 mL | 0.6397 mL | 1.5991 mL | |
| 60 mM | 0.0533 mL | 0.2665 mL | 0.5330 mL | 1.3326 mL | |
| 80 mM | 0.0400 mL | 0.1999 mL | 0.3998 mL | 0.9995 mL | |
| 100 mM | 0.0320 mL | 0.1599 mL | 0.3198 mL | 0.7996 mL |