NLRP3-IN-34
NLRP3-IN-34 (Compound T10) is an inhibitor for NLRP3 inflammasome. NLRP3-IN-34 inhibits ROS production, NLRP3 inflammasome-dependent IL-1β production (IC50 is 0.48 μM in cells J774A.1), and inhibits pyroptosis. NLRP3-IN-34 exhibits anti-inflammatory activity against DSS-induced peritonitis.
For research use only. We do not sell to patients.
- CAS No.: 1392502-55-4
- Formula: C26H22O6
- Molecular Weight:430.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1392502-55-4
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Molecular Weight 430.45
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Formula C26H22O6
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SMILES
CC1=COC2=C1C(C(C3=C2C=CC4=C3C(CCC4(C)C)OC(C5=C(C=CC=C5)O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)