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Cat. No.: HY-163497

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NLRP3-IN-38

NLRP3-IN-38 (Compound 18) is an inhibitor for NOD-like receptor protein 3 (NLRP3), that inhibits NLRP3 inflammasome activation with an EC₅₀ of 23 nM.

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CAS No.: 3033054-46-2
Formule: C₂₁H₂₁F₃N₄O₂
Masse moléculaire:418.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NLRP3-IN-38 Chemical Structure

CAS No.: 3033054-46-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

NLRP3-IN-38 (Compound 18) is an inhibitor for NOD-like receptor protein 3 (NLRP3), that inhibits NLRP3 inflammasome activation with an EC₅₀ of 23 nM^[1].

IC₅₀ & Target

NLRP3 inflammasome

23 nM (EC₅₀)

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Chemical Information

CAS No. 3033054-46-2
Masse moléculaire 418.41
Formule C₂₁H₂₁F₃N₄O₂
SMILES

C[C@H]1CN(C[C@H]([C@@H]1O)C)C2=C3C=NC=CC3=C(N=N2)C4=CC=C(C=C4O)C(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Donna A. A. W. HAYES, et al., Phthalazine derivatives useful as inhibitors of nod-like receptor protein 3. WO2024064245A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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NLRP3-IN-38

Voir tous les produits spécifiques à Isoform NOD-like Receptor (NLR)

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

NLRP3-IN-38 Related Classifications

HY-163497 Related Classifications

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