NLRP3-IN-74
NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 value of 2.7 μM. NLRP3-IN-74 can inhibit the release of IL-1β, reducing the release level by approximately 90%, and does not inhibit the release of TNFα. NLRP3-IN-74 can be used in the research of related diseases such as atherosclerosis and Parkinson's disease.
For research use only. We do not sell to patients.
- Formula: C20H22N4O4
- Molecular Weight:382.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NLRP3 2.7 μM (IC50) |
Chemical Information
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Molecular Weight 382.41
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Formula C20H22N4O4
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SMILES
O=C(N1C2CCN(C([C@@H](C)NC(C3=CC=CO3)=O)=O)CC2)NC4=C1C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-74 Related Classifications
HY-173294 Related Classifications
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