1. Others Antibody-drug Conjugate/ADC Related
  2. Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)
  3. NO2A-Azide trihydrochloride

NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

NO2A-Azide trihydrochloride

NO2A-Azide trihydrochloride Chemical Structure

CAS No. : 2435782-92-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

494.80

Formula

C15H30Cl3N7O5

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(O)CN1CCN(CC(O)=O)CCN(CC(NCCCN=[N+]=[N-])=O)CC1.Cl.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (101.05 mM; Need ultrasonic)

DMSO : 5 mg/mL (10.11 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0210 mL 10.1051 mL 20.2102 mL
5 mM 0.4042 mL 2.0210 mL 4.0420 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.0210 mL 10.1051 mL 20.2102 mL 50.5255 mL
5 mM 0.4042 mL 2.0210 mL 4.0420 mL 10.1051 mL
10 mM 0.2021 mL 1.0105 mL 2.0210 mL 5.0525 mL
H2O 15 mM 0.1347 mL 0.6737 mL 1.3473 mL 3.3684 mL
20 mM 0.1011 mL 0.5053 mL 1.0105 mL 2.5263 mL
25 mM 0.0808 mL 0.4042 mL 0.8084 mL 2.0210 mL
30 mM 0.0674 mL 0.3368 mL 0.6737 mL 1.6842 mL
40 mM 0.0505 mL 0.2526 mL 0.5053 mL 1.2631 mL
50 mM 0.0404 mL 0.2021 mL 0.4042 mL 1.0105 mL
60 mM 0.0337 mL 0.1684 mL 0.3368 mL 0.8421 mL
80 mM 0.0253 mL 0.1263 mL 0.2526 mL 0.6316 mL
100 mM 0.0202 mL 0.1011 mL 0.2021 mL 0.5053 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NO2A-Azide trihydrochloride
Cat. No.:
HY-W717800A
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