NS5818
NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potential for the research of osteoporosis.
For research use only. We do not sell to patients.
- CAS No.: 674299-39-9
- Formula: C23H19Cl2N7O2
- Molecular Weight:496.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NS5818 (50 µM; 6 days) inhibits acidification of the osteoclastic resorption compartment and bone resorption with an IC50 value of 5µM for bone resorption in human osteoclasts[1].
NS5818 (10 µM; 20 days) inhibits resorption in mature osteoclasts cultured on bovine bone slices[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 674299-39-9
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Molecular Weight 496.35
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Formula C23H19Cl2N7O2
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SMILES
O=C(C1=CC=C(C=C1)C2=CC=C(C=C2C3=NNN=N3)NC(NC4=CC(Cl)=CC(Cl)=C4)=O)N(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NS5818 Related Classifications
HY-122077 Related Classifications
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