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Cat. No.: HY-149608

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Nurr1 agonist 5

Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a K_d of 0.5 μM and an EC₅₀ of 3 μM.

For research use only. We do not sell to patients.

CAS No.: 3033875-32-7
Formula: C₁₉H₁₉Cl₂N₃O₂
Molecular Weight:392.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Nurr1 agonist 5 Chemical Structure

CAS No.: 3033875-32-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a K_d of 0.5 μM and an EC₅₀ of 3 μM^[1].

IC₅₀ & Target

Nurr1/NR4A2

All Nuclear Hormone Receptor 4A/NR4A Isoforms :

Chemical Information

CAS No. 3033875-32-7
Molecular Weight 392.28
Formula C₁₉H₁₉Cl₂N₃O₂
SMILES

ClC1=C(C=C2C(C=CN2)=C1)C(NC3=C(C=CC(Cl)=C3)OCCN(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Minh Sai, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023 Oct 12;66(19):13556-13567. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Nurr1 agonist 5

All Nuclear Hormone Receptor 4A/NR4A Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Nurr1 agonist 5 Related Classifications

HY-149608 Related Classifications

Bioz

Keywords

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