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Cat. No.: HY-149608

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Nurr1 agonist 5

Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a K_d of 0.5 μM and an EC₅₀ of 3 μM.

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CAS No.: 3033875-32-7
Formule: C₁₉H₁₉Cl₂N₃O₂
Masse moléculaire:392.28

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Nurr1 agonist 5 Chemical Structure

CAS No.: 3033875-32-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
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Calculators
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Description

Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a K_d of 0.5 μM and an EC₅₀ of 3 μM^[1].

IC₅₀ & Target

Nurr1/NR4A2

Voir tous les produits spécifiques à Isoform Nuclear Hormone Receptor 4A/NR4A :

Chemical Information

CAS No. 3033875-32-7
Masse moléculaire 392.28
Formule C₁₉H₁₉Cl₂N₃O₂
SMILES

ClC1=C(C=C2C(C=CN2)=C1)C(NC3=C(C=CC(Cl)=C3)OCCN(C)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Minh Sai, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023 Oct 12;66(19):13556-13567. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Nurr1 agonist 5

Voir tous les produits spécifiques à Isoform Nuclear Hormone Receptor 4A/NR4A

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Nurr1 agonist 5 Related Classifications

HY-149608 Related Classifications