Danvilostomig
Based on 1 Customer Validation
Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody.
For research use only. We do not sell to patients.
- Purity : 98.38%
- CAS No.: 2599198-80-6
- Molecular Weight:196.355 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
IgG1-kappa-[scFv]2-kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CTLA4 & PDCD1
Gene ID
Accession
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa-[scFv]2-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CTLA-4 Protein, Human (HEK293, HY-P72959) can bind Danvilostomig. The EC50 for this effect is 34.38 ng/mL. -
Immobilized PD-1 Protein, Human (147a.a, HEK293, His, HY-P70766) can bind Danvilostomig. The EC50 for this effect is 34.66 ng/mL. -
Flow cytometric analysis of 1X106 Jurkat cells labeling CTLA4 with Danvilostomig (HY-P990722, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2599198-80-6
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Appearance Liquid
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Molecular Weight 196.355 kDa
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Color Colorless to light yellow
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Danvilostomig
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)