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Cat. No.: HY-10016R

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E 2012 (Standard)

E 2012 (Standard) is the analytical standard of E 2012 (HY-10016). This product is intended for research and analytical applications. E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.

For research use only. We do not sell to patients.

CAS No.: 870843-42-8
Formula: C₂₅H₂₆FN₃O₂
Molecular Weight:419.49

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Please store the product under the recommended conditions in the Certificate of Analysis.

E 2012 (Standard) Chemical Structure

CAS No.: 870843-42-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 870843-42-8
Molecular Weight 419.49
Formula C₂₅H₂₆FN₃O₂
SMILES

O=C(N([C@H](C1=CC=C(C=C1)F)C)CCC/2)C2=C\C3=CC=C(N4C=NC(C)=C4)C(OC)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

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E 2012 (Standard)

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