Octahydroaminoacridine succinate

Cat. No.: HY-135006 Purity: 99.88%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Octahydroaminoacridine succinate, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. Octahydroaminoacridine succinate can be used for Alzheimer's disease (AD) research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Octahydroaminoacridine succinate 화학구조

CAS No. : 866245-79-6

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Octahydroaminoacridine succinate:

Octahydroaminoacridine 견적 받기

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•Related Small Molecules:

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View All Cholinesterase (ChE) Isoform Specific Products:

View All Isoforms

AChE BChE

Biological Activity
순도&문서
References
고객리뷰

제품 설명

분자량

320.38

화학식

C₁₇H₂₄N₂O₄

CAS No.

866245-79-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC(O)=O.NC1=C(CCCC2)C2=NC3=C1CCCC3

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 31.25 mg/mL (97.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1213 mL	15.6065 mL	31.2129 mL
5 mM	0.6243 mL	3.1213 mL	6.2426 mL
10 mM	0.3121 mL	1.5606 mL	3.1213 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 50% PEG300 50% Saline
Solubility: 10 mg/mL (31.21 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.88%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (254 KB) HNMR (251 KB) LCMS (90 KB)

Handling Instructions (2659 KB)

References

[1]. Jiangbin Han, et al. Quantitation of the tacrine analogue octahydroaminoacridine in human plasma by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2009 Sep 8;50(2):171-4. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1213 mL	15.6065 mL	31.2129 mL	78.0323 mL
	5 mM	0.6243 mL	3.1213 mL	6.2426 mL	15.6065 mL
	10 mM	0.3121 mL	1.5606 mL	3.1213 mL	7.8032 mL
	15 mM	0.2081 mL	1.0404 mL	2.0809 mL	5.2022 mL
	20 mM	0.1561 mL	0.7803 mL	1.5606 mL	3.9016 mL
	25 mM	0.1249 mL	0.6243 mL	1.2485 mL	3.1213 mL
	30 mM	0.1040 mL	0.5202 mL	1.0404 mL	2.6011 mL
	40 mM	0.0780 mL	0.3902 mL	0.7803 mL	1.9508 mL
	50 mM	0.0624 mL	0.3121 mL	0.6243 mL	1.5606 mL
	60 mM	0.0520 mL	0.2601 mL	0.5202 mL	1.3005 mL
	80 mM	0.0390 mL	0.1951 mL	0.3902 mL	0.9754 mL