Octahydroaminoacridine succinate

Cat. No.: HY-135006 Pureza: 99.88%: Ficha de datos
COA

SDS
Instrucciones de manejo
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Octahydroaminoacridine succinate, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. Octahydroaminoacridine succinate can be used for Alzheimer's disease (AD) research.

Para uso exclusivo en investigación. No vendemos a pacientes.

Octahydroaminoacridine succinate Estructura química

No. CAS : 866245-79-6

Tamaño	Stock	Cantidad

Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Other Forms of Octahydroaminoacridine succinate:

Octahydroaminoacridine Obtener un presupuesto

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Cholinesterase (ChE):

Ver todas las isoformas

AChE BChE

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

Peso molecular

320.38

Fòrmula

C₁₇H₂₄N₂O₄

No. CAS

866245-79-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC(O)=O.NC1=C(CCCC2)C2=NC3=C1CCCC3

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : 31.25 mg/mL (97.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1213 mL	15.6065 mL	31.2129 mL
5 mM	0.6243 mL	3.1213 mL	6.2426 mL
10 mM	0.3121 mL	1.5606 mL	3.1213 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 50% PEG300 50% Saline
Solubility: 10 mg/mL (31.21 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.88%

Select Batch:

Ficha de datos (275 KB) SDS (251 KB)

COA (254 KB) HNMR (251 KB) LCMS (90 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Jiangbin Han, et al. Quantitation of the tacrine analogue octahydroaminoacridine in human plasma by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2009 Sep 8;50(2):171-4. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1213 mL	15.6065 mL	31.2129 mL	78.0323 mL
	5 mM	0.6243 mL	3.1213 mL	6.2426 mL	15.6065 mL
	10 mM	0.3121 mL	1.5606 mL	3.1213 mL	7.8032 mL
	15 mM	0.2081 mL	1.0404 mL	2.0809 mL	5.2022 mL
	20 mM	0.1561 mL	0.7803 mL	1.5606 mL	3.9016 mL
	25 mM	0.1249 mL	0.6243 mL	1.2485 mL	3.1213 mL
	30 mM	0.1040 mL	0.5202 mL	1.0404 mL	2.6011 mL
	40 mM	0.0780 mL	0.3902 mL	0.7803 mL	1.9508 mL
	50 mM	0.0624 mL	0.3121 mL	0.6243 mL	1.5606 mL
	60 mM	0.0520 mL	0.2601 mL	0.5202 mL	1.3005 mL
	80 mM	0.0390 mL	0.1951 mL	0.3902 mL	0.9754 mL