Octanoate, 99% sodium
Based on 3 publication(s) in Google Scholar
Octanoate, 99% sodium is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoate, 99% sodium is also an orally active tremor-suppressing agent.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 1984-06-1
- Formula: C8H15NaO2
- Molecular Weight:166.19
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Octanoate, 99% sodium
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Customer Validation & Images
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Cell Proliferation/Viability Assay
Biological Activity
Octanoate, 99% sodium (0-0.5 mM, 0.5 h) potentiates glucose-stimulated insulin secretion (GSIS) in MIN6 cells, via Olfr15 though the PLC-IP3 pathway[4].
Octanoate, 99% sodium (0-10 mM, 48 h) induces neurite outgrowth in PC12 cells, and activates p38 MAPK and ERK pathways[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:PC12 cells
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Concentration:3 mM
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Incubation Time:0-24 h
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Result:Increased p38 MAPK, ERK, and JNK level.
Octanoate, 99% sodium (150 mg/kg, oral gavage) shows protective effects in the mouse model of PD induced by MPTP (HY-15608)[2].
Octanoate, 99% sodium (1.3 mg, p.o.) promotes branched-chain amino acid (BCAA) catabolism in rats by activating BCKDC via decreasing the bound form of BCKDH kinase (BDK)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1984-06-1
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Appearance Solid
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Molecular Weight 166.19
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Formula C8H15NaO2
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Color White to off-white
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SMILES
[Na].O=C(O)CCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (3)
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Journal Impact Factor
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Most Recent
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Mol Cell
CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity. [Abstract]2023 Dec 7;83(23):4370-4385.e9. PMID: 38016475 -
Nutrients
Medium-Chain Fatty Acids Selectively Sensitize Cancer Cells to Ferroptosis by Inducing CD36 and ACSL4. [Abstract]2025 Feb 25;17(5):794. PMID: 40077664
Octanoate, 99% sodium purchased from MedChemExpress. Usage Cited in: Nutrients. 2025 Feb 25;17(5):794. [Abstract]
Compared with the untreated group, Octanoic acid (OA-m) (200 μM; 24 h), DA-m or LA-l alone did not significantly affect cell viability. However, the combination of OA-m with LA-l decreased U937 cell viability to 70.7%.
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Biochem Biophys Res Commun
2026 Mar 12:804:153358. PMID: 41619507
Octanoate, 99% sodium purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2026 Mar 12:804:153358. [Abstract]
Effects of Octanoic acid (OA) (100, 150, 200 μM; 24 h) on the expression of the fructose transporter GLUT5 and ketohexokinase (KHK) in IEC-18 intestinal epithelial cells.
Solvent & Solubility
H2O : 100 mg/mL (601.72 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Nahab FB, et al. Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. Neurotherapeutics. 2012 Jul;9(3):635-8. [Content Brief]
[2]. Joniec-Maciejak I, et al. Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease. Pharmacol Rep. 2018 Oct;70(5):988-992. [Content Brief]
[3]. Kadota Y, et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. Metabolism. 2015 Sep;64(9):1157-64. [Content Brief]
[4]. Leem J, et al. Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells. Biochem Biophys Res Commun. 2018 Sep 3;503(1):278-284. [Content Brief]
[5]. Kamata Y, et al. Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid. Neuroscience. 2007 May 25;146(3):1073-81. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.0172 mL | 30.0860 mL | 60.1721 mL | 150.4302 mL |
| 5 mM | 1.2034 mL | 6.0172 mL | 12.0344 mL | 30.0860 mL | |
| 10 mM | 0.6017 mL | 3.0086 mL | 6.0172 mL | 15.0430 mL | |
| 15 mM | 0.4011 mL | 2.0057 mL | 4.0115 mL | 10.0287 mL | |
| 20 mM | 0.3009 mL | 1.5043 mL | 3.0086 mL | 7.5215 mL | |
| 25 mM | 0.2407 mL | 1.2034 mL | 2.4069 mL | 6.0172 mL | |
| 30 mM | 0.2006 mL | 1.0029 mL | 2.0057 mL | 5.0143 mL | |
| 40 mM | 0.1504 mL | 0.7522 mL | 1.5043 mL | 3.7608 mL | |
| 50 mM | 0.1203 mL | 0.6017 mL | 1.2034 mL | 3.0086 mL | |
| 60 mM | 0.1003 mL | 0.5014 mL | 1.0029 mL | 2.5072 mL | |
| 80 mM | 0.0752 mL | 0.3761 mL | 0.7522 mL | 1.8804 mL | |
| 100 mM | 0.0602 mL | 0.3009 mL | 0.6017 mL | 1.5043 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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