OncoFAP-GlyPro-MMAE
Based on 1 Customer Validation
OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. OncoFAP-GlyPro-MMAE consists of a FAP Ligand OncoFAP (HY-145938), a Tubulin inhibitor (MMAE) (HY-15162) and a linker. OncoFAP-GlyPro-MMAE can be used for cancers like renal cancer research.
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 2688118-55-8
- Formula: C102H141F2N19O27S
- Molecular Weight:2135.38
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2688118-55-8
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Appearance Solid
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Molecular Weight 2135.38
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Formula C102H141F2N19O27S
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Color Off-white to light yellow
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SMILES
O=C(NCC(N1[C@H](C#N)CC(F)(F)C1)=O)C2=CC=NC3=C(NC(CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CSC4C(N(CCCCCC(NCC(N5[C@H](C(NC6=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N7[C@](CCC7)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C8=CC=CC=C8)O)=O)=O)=O)=O)=O)C=C6)=O)CCC5)=O)=O)C(C4)=O)=O)=O)=O)=O)=O)=O)C=CC=C32
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Synonyms
OncoFAP glidotin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (46.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.4683 mL | 2.3415 mL | 4.6830 mL | 11.7075 mL |
| 5 mM | 0.0937 mL | 0.4683 mL | 0.9366 mL | 2.3415 mL | |
| 10 mM | 0.0468 mL | 0.2342 mL | 0.4683 mL | 1.1708 mL | |
| 15 mM | 0.0312 mL | 0.1561 mL | 0.3122 mL | 0.7805 mL | |
| 20 mM | 0.0234 mL | 0.1171 mL | 0.2342 mL | 0.5854 mL | |
| 25 mM | 0.0187 mL | 0.0937 mL | 0.1873 mL | 0.4683 mL | |
| 30 mM | 0.0156 mL | 0.0781 mL | 0.1561 mL | 0.3903 mL | |
| 40 mM | 0.0117 mL | 0.0585 mL | 0.1171 mL | 0.2927 mL |
OncoFAP-GlyPro-MMAE Related Classifications
HY-175350 Related Classifications
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