1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. Oxotremorine sesquifumarate

Oxotremorine sesquifumarate 

Cat. No.: HY-101239 Purity: ≥98.0%
Handling Instructions

Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research.

For research use only. We do not sell to patients.

Oxotremorine sesquifumarate Chemical Structure

Oxotremorine sesquifumarate Chemical Structure

CAS No. : 17360-35-9

Size Price Stock Quantity
5 mg USD 72 In-stock
Estimated Time of Arrival: December 31
10 mg USD 115 In-stock
Estimated Time of Arrival: December 31
25 mg USD 230 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2].

In Vitro

Oxotremorine (10.5 μM) produces a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In rats with sciatic nerve injuries, Oxotremorine (10, 5, 2 1 μg; 10 μL) i.t. dose-dependently suppresses the tactile hypersensitivity[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

380.40

Formula

C₁₆H₂₂N₂O₅

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (328.60 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6288 mL 13.1441 mL 26.2881 mL
5 mM 0.5258 mL 2.6288 mL 5.2576 mL
10 mM 0.2629 mL 1.3144 mL 2.6288 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.57 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.47 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.47 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Oxotremorine sesquifumarate
Cat. No.:
HY-101239
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