Muscarine iodide
Based on 1 publication(s) in Google Scholar
Muscarine ((+)-Muscarine) iodide is a toxin that can stimulate the parasympathetic nervous system. Muscarine iodide is a prototype muscarinic acetylcholine receptor agonist.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 24570-49-8
- Formula: C9H20INO2
- Molecular Weight:301.17
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Muscarine iodide
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Biological Activity
Muscarine iodide administration (100 μM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 μM ACh[1].Muscarine iodide (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 24570-49-8
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Appearance Solid
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Molecular Weight 301.17
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Formula C9H20INO2
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Color White to off-white
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SMILES
C[N+](C)(C)C[C@@H]1C[C@@H](O)[C@H](C)O1.[I-]
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Synonyms
(+)-Muscarine iodide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Cancer Cell
2025 Aug 12:S1535-6108(25)00330-7. PMID: 40829591
Solvent & Solubility
H2O : 50 mg/mL (166.02 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. [Content Brief]
[2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.3204 mL | 16.6019 mL | 33.2038 mL | 83.0096 mL |
| 5 mM | 0.6641 mL | 3.3204 mL | 6.6408 mL | 16.6019 mL | |
| 10 mM | 0.3320 mL | 1.6602 mL | 3.3204 mL | 8.3010 mL | |
| 15 mM | 0.2214 mL | 1.1068 mL | 2.2136 mL | 5.5340 mL | |
| 20 mM | 0.1660 mL | 0.8301 mL | 1.6602 mL | 4.1505 mL | |
| 25 mM | 0.1328 mL | 0.6641 mL | 1.3282 mL | 3.3204 mL | |
| 30 mM | 0.1107 mL | 0.5534 mL | 1.1068 mL | 2.7670 mL | |
| 40 mM | 0.0830 mL | 0.4150 mL | 0.8301 mL | 2.0752 mL | |
| 50 mM | 0.0664 mL | 0.3320 mL | 0.6641 mL | 1.6602 mL | |
| 60 mM | 0.0553 mL | 0.2767 mL | 0.5534 mL | 1.3835 mL | |
| 80 mM | 0.0415 mL | 0.2075 mL | 0.4150 mL | 1.0376 mL | |
| 100 mM | 0.0332 mL | 0.1660 mL | 0.3320 mL | 0.8301 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Muscarine iodide Related Classifications
HY-107654 Related Classifications
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