Muscarine tosylate
Based on 1 publication(s) in Google Scholar
Muscarine ((+)-Muscarine) tosylate is an agonist of prototype mAChR. Muscarine tosylate is a toxin that can stimulate the parasympathetic nervous system.
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- CAS No.: 82083-43-0
- 화학식: C16H27NO5S
- 분자량:345.45
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보관:
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Biological Activity
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Chemical Information
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Biological Activity
제품 설명
In Vitro
Muscarine tosylate (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM acetylcholine in brain miero vascular endothelial cells (BMVECs) and brain-derived Endothelial cells.3 (bEnd.3)[1].
Muscarine tosylate (1-30 μM; 2 min) produces a dose-dependent hyperpolarization in a sub-population of the nucleus raphe magnus (NRM) cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons with an EC50 value of 2.7 µM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 82083-43-0
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분자량 345.45
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화학식 C16H27NO5S
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SMILES
C[N+](C)(C)C[C@@H]1C[C@H]([C@@H](O1)C)O.O=S([O-])(C2=CC=C(C=C2)C)=O
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Synonyms
(+)-Muscarine tosylate
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cancer Cell
2025 Nov 10;43(11):2089-2105.e10. PMID: 40829591
순도&문서
References
[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083. [Content Brief]
[2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Muscarine tosylate Related Classifications
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