1. GPCR/G Protein Neuronal Signaling
  2. mAChR
  3. Muscarine tosylate

Muscarine tosylate  (Synonyms: (+)-Muscarine tosylate)

Cat. No.: HY-121404B
Handling Instructions

Muscarine ((+)-Muscarine) tosylate is an agonist of prototype mAChR. Muscarine tosylate is a toxin that can stimulate the parasympathetic nervous system.

For research use only. We do not sell to patients.

Muscarine tosylate Chemical Structure

Muscarine tosylate Chemical Structure

CAS No. : 82083-43-0

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Description

Muscarine ((+)-Muscarine) tosylate is an agonist of prototype mAChR. Muscarine tosylate is a toxin that can stimulate the parasympathetic nervous system[1][2].

In Vitro

Muscarine tosylate (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM acetylcholine in brain miero vascular endothelial cells (BMVECs) and brain-derived Endothelial cells.3 (bEnd.3)[1].
Muscarine tosylate (1-30 μM; 2 min) produces a dose-dependent hyperpolarization in a sub-population of the nucleus raphe magnus (NRM) cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons with an EC50 value of 2.7 µM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

345.45

Formula

C16H27NO5S

CAS No.
SMILES

C[N+](C)(C)C[C@@H]1C[C@H]([C@@H](O1)C)O.O=S([O-])(C2=CC=C(C=C2)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Muscarine tosylate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Muscarine tosylate
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HY-121404B
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