P2Y1 antagonist 3
P2Y1 antagonist 3 (compound 36b) is a blood-brain barrier (BBB)-penetrant P2Y1 antagonist with an IC50 of 0.50 μM. P2Y1 antagonist 3 exhibits protective effects in a rat middle cerebral artery occlusion (MCAO) model and demonstrates neuroprotective activity against oxidative stress by upregulating nuclear Nrf2 protein levels.
For research use only. We do not sell to patients.
- Formula: C19H10N4O3
- Molecular Weight:342.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All P2Y Receptor Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 342.31
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Formula C19H10N4O3
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SMILES
OC(C1=CN=C(C2=CC=CC(C#N)=C2)N=C1OC3=CC=CC(C#N)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)