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Cat. No.: HY-175913

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PAPD5 ligand-1

PAPD5 ligand-1 is a PAPD5 ligand, which can be used for the synthesis of PROTACs, such as PROTAC PAPD5 degrader 1 (HY-162327).

For research use only. We do not sell to patients.

Formula: C₂₁H₂₆N₂O₅
Molecular Weight:386.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PAPD5 ligand-1 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PAPD5 ligand-1 is a PAPD5 ligand, which can be used for the synthesis of PROTACs, such as PROTAC PAPD5 degrader 1 (HY-162327)^[1].

IC₅₀ & Target^[1]

PAPD5

Chemical Information

Molecular Weight 386.44
Formula C₂₁H₂₆N₂O₅
SMILES

O=C(C1=CN([C@H](C(C)C)CC2=C3C=C(OC)C(OCCCN)=C2)C3=CC1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. You Li, et al. “PROTAC” modified Dihydroquinolizinones (DHQs) that causes degradation of PAPD-5 and inhibition of hepatitis a virus and hepatitis B virus, in vitro. Bioorg Med Chem Lett. 2024 Feb 29:102:129680. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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