PD-1-IN-25
PD-1-IN-25 (compound 43) is a potent PD-1/PD-L1 interaction inhibitor with an IC50 value of 10.2 nM in the HTRF assay. PD-1-IN-25 can promote CD8+ T cell activation through inhibiting PD-1/PD-L1 cellular signaling. PD-1-IN-25 delays the tumor growth.
For research use only. We do not sell to patients.
- CAS No.: 2413100-40-8
- Formula: C37H35ClF2N2O9
- Molecular Weight:725.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2413100-40-8
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Molecular Weight 725.13
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Formula C37H35ClF2N2O9
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SMILES
CC1=C(C=CC=C1C(F)(F)OC2=CC(OCC3=CC(C#N)=CC=C3)=C(C=C2Cl)CN[C@H]4[C@H]([C@@H]([C@H](OC4O)CO)O)O)C5=CC=C(OCCO6)C6=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)